Cloud Platforms: The Crucial Foundation to Safeguard the Pharmaceutical
In today's pharmaceutical supply chain, counterfeit activity is thriving. As
pharma companies have expanded target markets and outsourced production over
the last decade, the supply chain has become increasingly global, virtual,
and vulnerable. Illicit activity has thrived, and patients have suffered,
with hundreds of thousands dying each year from counterfeit and contaminated
More than 40 countries have responded with new laws that regulate
prescription medications as they travel through the supply chain. While this
is a quantum leap forward for patient health, the implications for supply
chain stakeholders, from pharmaceutical companies and their contract
manufacturing partners to the pharmacies that serve patients are daunting:
they must master each country's disparate t... (more)
It should come as no surprise that more and more organizations are focused on
meeting customer service expectations, guaranteeing end-to-end business
process delivery and modernizing their IT infrastructures. But what does
this mean for IT operations teams?
If we approach this question using an iceburg analogy, the tip would probably
be an easy observation, such as “IT operations needs to adopt a
business-centric way of thinking.” But dealing with all the change that
needs to occur beneath the surface of this statement is what can sink or
float an organization. IT operations teams need to start breaking down the
internal silos, and learn to paddle their canoe in the same direction. They
need to figure out a whole new approach to IT management with challenges that
range from how best to work with emerging IT teams responsible for virtual or
Cloud-based environment... (more)
Cloud computing is the hottest topic in IT. Gartner ranks cloud in the #1
spot of its list of top 10 strategic technology topics. It is the overriding
theme at most industry conferences this year. Projections of cloud revenue
growth rates in the high double digits further underscore the relevance of
Yet today’s discussions of cloud computing only hint at its full potential.
Like the early days of e-business and the introduction of SOA, cloud is in
its infancy, with its promise still to be fully realized. Advocates of cloud
are limiting their focus to tactical cost benefits and efficiency gains on
the IT infrastructure side, but the real benefit of cloud computing will be
realized within the context of future developments that will shape the course
of IT. When combined with these developments, cloud computing will become
part of an innovation that changes... (more)
CTP2 offers customers an opportunity to evaluate both System Center 2012 and
Windows Server 2012, both are the enabling technologies for constructing
private cloud with hybrid scenarios. There are important updates and
enhancements to System Center 2012 components and this post is a quick
reference as listed below. Notice that pertinent information of all
components is in the technical documentation of the CTP2 release of System
Center 2012 SP1. There is also much information in TechNet library.
This is an add-on of SCVMM 2012 and a web-based interface configured as a
virtual directory in IIS and offers a single pane of glass to manage both
public and private clouds. It is a strategic tool to delegate cloud resources
management with a self-service role-based security model.
With Service Provider Foundation API t... (more)
If cloud computing is going to spread to more mission-critical type
applications, it needs to get more accurate when it comes to
transaction-based applications. Trying to keep everything in a structured
framework is going to require a more rigorous network infrastructure that
includes timing down to milliseconds, if not nanoseconds.
One way to accomplish this is to use the IEEE 1588 protocol or "Precision
Time Protocol" (PTP), which provides timing. In an earlier article entitled,
"Cloud Transaction Synchronicity," I discussed the need for this type of
capability if financial organizations are to look at cloud computing as a
real solution for any transactions-based services.
When It Comes to Mission Critical, Timing Is Everything
Few talk about this essential need because few understand what makes "the
cloud" work. Any vendor or system architect always draws "the Clou... (more)
Over the past few months, I have interacted with several organizations that
are evaluating changes to their business model to adapt to the cloud-enabled
IT ecosystem. Management is in a quandary over maintaining their profitable
lines of business while growing revenue in new and emerging areas. The
problem they face is that some emerging business lines are only possible with
completely revamped business models requiring significant change.
Some very large organizations, like Dell, are taking the significant step of
going private to enhance the transformation process outside the public eye of
investors. New leaders, like Amazon and Salesforce, are disrupting the market
with their infrastructure and software "as a service" offerings.
Organizations eager to get a jump-start are leveraging these services to
create new offerings. But companies interested in transforming t... (more)
"This excerpt is from the book, "Systems Performance: Enterprise and the
Cloud", authored by Brendan Gregg, published by Prentice Hall Professional,
Oct. 2013, ISBN 9780133390094, Copyright © 2014 Pearson Education, Inc. For
more info, please visit the publisher site:
CPUs drive all software and are often the first target for systems
performance analysis. Modern systems typically have many CPUs, which are
shared among all running software by the kernel scheduler. When there is more
demand for CPU resources than there are resources available, process threads
(or tasks) will queue, waiting their turn. Waiting can add significant
latency during the runtime of applications, degrading performance.
The usage of the CPUs can be examined in detail to look for performance
improvements, including eliminating unnecessary work. At a high level, CPU
usage by process, thread, or ... (more)
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This Lab Validation report from Enterprise Strategy Group (ESG) provides you
with best practices to create an environment that offers you simple unified
data protection across physical and virtual landscapes, maximum protection
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INETCO Systems Limited, a provider of transaction-based application
performance monitoring solutions, today announced Transaction Junction, a
subsidiary of Blue Label Telecoms (JSE:BLU), has chosen INETCO Insight to
improve operational efficiency and gain better visibility into the customer
experience. Blue Label Telecoms will also use INETCO Insight to monitor its
mobile pre-paid air time program currently being rolled out in thousands of
retail locations across Africa, Mexico, India and China.
Transaction Junction provides electronic funds transfer (EFT) and a wide
variety of value-added service (VAS) transaction management solutions to the
Southern Africa and global market sectors. By guaranteeing all credit,
debit, lotto ticketing, bill payment, prepaid electricity and prepaid mobile
air time transactions are secure and reliable, Transaction Junction enables
I recently moderated a webinar where Loki Jorgenson, a technical advisor to
INETCO, did an outstanding job of answering this question.
The take-away goods:
According to a recent report by Trac Research comparing infrastructure
approaches to transactional approaches - 81% of companies still focus on
infrastructure reports, with only 39% adopting application transaction views
on application performance. Yet times to resolve issues arising in
multi-tiered application environments took 112 minutes on average using an
infrastructure approach to solve the problem, compared to 31 minutes for a
These figures indicate that transaction-based application performance
monitoring (APM) is becoming more essential - but they also indicate
wide-spread adoption is still in the works and companies are taking their
time. Can they afford to?
Let's take a moment... (more)